CUH seeks rental of high sensitivity LC-TMS for hormone and newborn screening analysis.
Some language patterns suggest this RFP may be written for a specific incumbent vendor. Review qualification requirements and brand-specific terms carefully before committing bid resources.
Cambridge University Hospitals NHS Foundation Trust seeks to replace a high sensitivity Triple Quadrupole Tandem Mass Spectrometer (TMS) coupled to an HPLC system for the Blood Sciences Biochemical Genetics Unit. The system runs 10 methods including newborn blood spot analysis, processing ~120,000 samples/year across four LC-TMS systems. The replacement must be capable of quantitating metabolites in human serum, urine, and blood spots at nmol/L concentrations, using Chemoview for newborn screening. Critical requirements include multiple scan modes, APCI and ESI ionization, polarity switching, compatibility with multi-vendor HPLC, oil-free pump, and direct transferability of current methods. The HPLC must have dual binary pump arrangement up to 10,000 PSI, online SPE, and autosampler with multiple plate/vial positions. This is a direct award notice, suggesting a sole-source or incumbent replacement.